isotype species Search Results


monoclonal igg2a isotype control  (R&D Systems)
90
R&D Systems monoclonal igg2a isotype control
Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or <t>IgG</t> isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).
Monoclonal Igg2a Isotype Control, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/isotype+species/Non-species+specific+IgG2a+Isotype+Control+(IGG2a%2F6723)/pmc07431826-163-11-15
Average 90 stars, based on 1 article reviews
monoclonal igg2a isotype control - by Bioz Stars, 2026-10
90/100 stars
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species-specific isotype control  (Immunex Corporation)
90
Immunex Corporation species-specific isotype control
Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or <t>IgG</t> isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).
Species Specific Isotype Control, supplied by Immunex Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/isotype+species/species+specific+isotype+control+antibody/10__1182_slash_blood__v89__3__910-50-49-52
Average 90 stars, based on 1 article reviews
species-specific isotype control - by Bioz Stars, 2026-10
90/100 stars
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fitc- pe conjugated isotype-matched control antibodies irrelevant speci®city  (Becton Dickinson)
90
Becton Dickinson fitc- pe conjugated isotype-matched control antibodies irrelevant speci®city
Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or <t>IgG</t> isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).
Fitc Pe Conjugated Isotype Matched Control Antibodies Irrelevant Speci®City, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/isotype+species/fitc++pe+conjugated+isotype+matched+control+antibodies+irrelevant+speci+city/pm11573204-68-13-14
Average 90 stars, based on 1 article reviews
fitc- pe conjugated isotype-matched control antibodies irrelevant speci®city - by Bioz Stars, 2026-10
90/100 stars
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species isotype  (Interchim Chemicals)
86
Interchim Chemicals species isotype
Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or <t>IgG</t> isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).
Species Isotype, supplied by Interchim Chemicals, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/isotype+species/isotype+species+specific/pmc05433753-60-0-8
Average 86 stars, based on 1 article reviews
species isotype - by Bioz Stars, 2026-10
86/100 stars
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non-species specific igg2a isotype control (igg2a/6723) [alexa fluor® 647]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [Alexa Fluor® 647]
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non-species specific igg2a isotype control (igg2a/6723) [alexa fluor® 750]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [Alexa Fluor® 750]
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non-species specific igg2a isotype control (igg2a/6723) [pe]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [PE]
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non-species specific igg2a isotype control (igg2a/6723) [mfluor violet 610 se]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [mFluor Violet 610 SE]
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non-species specific igg2a isotype control (igg2a/6723) [dylight 350]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [DyLight 350]
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non-species specific igg2a isotype control (igg2a/6723) [dylight 550]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [DyLight 550]
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non-species specific igg2a isotype control (igg2a/6723)  (Novus Biologicals)
N/A
The Non-species specific IgG2a Isotype Control (IGG2a/6723) from Novus is a IgG2a antibody to IgG2a. This antibody reacts with Non-species specific. The IgG2a antibody has been validated for the following applications: Western Blot, Flow Cytometry,
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non-species specific igg2a isotype control (igg2a/6723) [biotin]  (Novus Biologicals)
N/A
Non-species specific IgG2a Isotype Control (IGG2a/6723) [Biotin]
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Image Search Results


Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or IgG isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).

Journal: Aging Cell

Article Title: The aged hematopoietic system promotes hippocampal‐dependent cognitive decline

doi: 10.1111/acel.13192

Figure Lengend Snippet: Cyclophilin A regulates cellular and cognitive hallmarks of hippocampal aging. (a) Schematic showing hydrodynamic tail vein injection (HDTVI)‐mediated CyPA overexpression (OE) paradigm in young mice. (b–d) Young CyPA‐OE or GFP control mice were tested in novel object recognition (b; NOR; n = 8–12/group), contextual fear conditioning (c; FC; n = 15–16), and cued FC (d; n = 15–16). (e, f) Representative fields (e; scale bar = 100 μm) and quantification (f) of DCX+ cells ( n = 11/group), in DG of young CyPA‐OE and GFP control mice. (g, h) Representative Western blot (g) and quantification (h) of hippocampal lysates from young CyPA‐OE and GFP control mice, probed with anti‐NR2B, synapsin‐1 (Syn‐1), synaptophysin (Syp), and GAPDH ( n = 5/group). (i) Schematic showing CyPA inhibition paradigm in aged mice. (j–l) Aged mice treated with an anti‐CyPA antibody or IgG isotype control (ctrl) were tested in NOR (j; n = 10–14/group), contextual FC (k; n = 10–14/group), and cued FC (l; n = 10–14/group). (m, n) Representative fields (m; scale bar = 100 μm) and quantification (n) of DCX+ ( n = 8–10/group), in anti‐CyPA or IgG ctrl‐treated old mice. (o, p) Representative Western blot (o) and quantification (p) of hippocampal lysates from anti‐CyPA or IgG ctrl‐treated old mice, probed with anti NR2A, Syn‐1, Syp, and GAPDH ( n = 5/group). All data shown as the mean + SEM . *p < 0.05. t test (c, d, f, h, k, l, n, p). One‐sample t test vs. hypothetical mean of 50 (b, j).

Article Snippet: The anti‐CyPA antibody, 8H7 (Von Ungern‐Sternberg et al., ), or a monoclonal IgG2A isotype control (R&D Systems) was intraperitoneally administered to aged (19 months) mice (20 μg/kg).

Techniques: Injection, Over Expression, Control, Western Blot, Inhibition